Everybody reacts differently. Some guys get real horny, some get a headach, others lose their erection (it lowers blood pressure....necessary to maintain an erection
) and some get a good (but short lived...less than 30 seconds) head rush. If you can time the rush with your orgasim, it can be great.
My favorite is Amsterdam poppers followed by Jungle Juice. Both are sold in the brown bottle. I tried the kind that comes in a spray can and it actually made me nauseous.......thought I was going to vomit. The first time or two with the brown bottle resulted in a headach for me, but since then no problrm. So give them a try, maybe more than once, and see how it affects you.